Not all possible drug interactions are listed here. 5 0 obj Learn more about these, as well as the symptoms, diagnosis, and treatments. Orofer S 50 Injection 1 Injection in 1 Packet 147. In the first group, some people continued taking iron by mouth, while other people took Injectafer. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. Diarrhea. 3 0 obj With anemia, you have a low level of red blood cells (RBCs) in your body. Your doctor will go over your For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. But keep in mind that in this study, delayed allergic reaction only occurred in one person. Or your doctor may recommend that you change your eating habits to include more iron in your diet. Nose or throat irritation. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. What is the latest research on the form of cancer Jimmy Carter has? Do not exceed 1,500 mg of iron per dosing course. Its not known whether its safe to breastfeed while youre taking Injectafer. Excessive amounts of Venofer may lead to a condition called iron overload, which may be harmful. There are different types of anemia, but IDA is the most common type. The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. People with IDA have low blood levels of hemoglobin. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. Procedure Details Some people only need one treatment course of Injectafer. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. Its possible that after getting two doses of Injectafer, your anemia may go away completely. The following information is provided for clinicians and other healthcare professionals. Storage Condition Store in a cool and dry place protected from light. Best food forward: Are algae the future of sustainable nutrition? However, consuming large amounts of alcohol can actually cause anemia in some people. Should I avoid certain foods while taking Venofer Vial? However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. You may report side effects to Health Canada at 1-866-234-2345. This is not a complete list of side effects and others may occur. These lists dont include all possible side effects. The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. After the infusion, you can drive yourself home and return to your usual activities. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. As a result, you may not make as much EPO as usual. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. Learn about uses, cost, how it works, and more. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] So theres no recommended pediatric dosage for Injectafer. This website is intended for use by US patients. Hemoglobin is a protein thats found in your RBCs. In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. This test measures the amount of hemoglobin in your blood. Infusion times range from less than 20 minutes to up to 4 hours. And this can lead to anemia, including IDA. You should not receive Venofer if you have known allergies to iron sucrose. Copyright 1996-2023 Cerner Multum, Inc. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. If youre wondering how longside effectslast, youll be happy to know they can last just a few hours. Injectafer is approved to treat iron deficiency anemia (IDA). Its not currently available in generic form. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. HRT, like other medications, does have some side effects and these are thought to be quite common. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. %PDF-1.3 Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. Tell your doctor if you are taking iron supplements or other iron-based oral medications. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Injectafer and Venofer can cause very similar side effects, but some different ones as well. Mild side effects of Injectafer can include:*. It's a more immediate treatment than supplements or dietary changes. Its responsible for carrying oxygen throughout your body. Pain, swelling, or redness at the injection site may occur. Review our medical disclaimer. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. Venofer infusions- how long does it take to notice improvement?? - Reddit Keep all drugs out of the reach of children and pets. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). The study also didnt show if one treatment was worse than the other. Tell all of your health care providers that you take Venofer. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. If either is present, do not use the liquid. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. Canada residents can call a provincial poison control center. It depends. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. Feeling awful 10 days after Iron Infusion. Is it normal? Remember that it is best to get your vitamins and minerals from food whenever possible. Hes an expert in genetic testing, genetic analysis, andprecision medicine. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. Reblozyl is a brand-name prescription medication used to treat anemia in certain blood disorders. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Injectafer contains the active drug ferric carboxymaltose. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; Venofer intravenous: Uses, Side Effects, Interactions & Pill - RxList In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. Allergic reactions typically occur the first time your body is exposed to a drug. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. Answer by DrLact: About Venofer usage in lactation. Call your doctor for medical advice about side effects. <> If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. Keep in mind that the risk of certain pregnancy-related problems can be increased if iron deficiency anemia (IDA) is left untreated. PDF Protocol for the use of Intravenous Iron Sucrose (Venofer A variety of tests can diagnose iron deficiency anemia. I was surprised too but the Dr said it definitely sounds like a reaction. The oral form of the drug, called sucroferric oxyhydroxide and used . If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). pain in the arms or legs. 4 0 obj Notify your healthcare provider of any irritation at the injection site. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. This includes your doctors, nurses, pharmacists, and dentists. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. ByDr. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. What are the side effects of Venofer? Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. dizziness. Venofer Intravenous: Uses, Side Effects, Interactions, Pictures - WebMD WebMD provides common contraindications for Venofer Vial. Properly discard this product when it is expired or no longer needed. Understanding what thoseside effectsare can lead to a strategy to prevent them. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. With a delayed reaction, your body reacts to a drug that youve been exposed to in the past without having a reaction. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. Its not known how often people taking a treatment other than Injectafer had diarrhea. Common and Rare Side Effects for Venofer Vial - WebMD In clinical trials,. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). Do not flush down a toilet or pour down a drain unless you are told to do so. A healthcare provider will give you this injection. This survey is being conducted by the WebMD marketing sciences department. 2023 Medicine.com All rights reserved. A lack of iron can lead to iron deficiency anaemia if left untreated. For example: Say you weigh 105 pounds (about 48 kilograms). With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. What to Know About Iron Infusions for Anemia Treatment - GoodRx These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. Its possible to get rid of or reduce the severity ofside effects. Details. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. Side effects are uncomfortable reactions to medications or drugs. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. There may be drug take-back programs in your area. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). These people may lose weight as their anemia improves because theyre more active. Details. (IV iron is absorbed by the body more rapidly than oral iron.) No, you wont need to take iron pills while youre using Injectafer. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. This medication passes into breast milk. Venofer - Iron sucrose uses, dose and side effects - zeepedia.com Is the ketogenic diet right for autoimmune conditions? Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. These nutrients include iron, vitamin B12, and folate. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. PDF Venofer - Food and Drug Administration To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. Very bad and sometimes deadly allergic side effects have rarely happened. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. (A medication class is a group of medications that work in a similar way.). If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. 2005 - 2023 WebMD LLC. Theseside effectscan range from being mild tosevere. For additional information, contact your healthcare provider. Examples of these side effects include dizziness and nausea. Examples of thisinclude: Not allside effectslast forever. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. Does Venofer Vial interact with other medications? Last updated August 20, 2020. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. Last updated on Feb 20, 2023. For people with certain medical implants, such as pacemakers, an MRI may pose an . The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Keep all regular medical and laboratory appointments. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. Cardiovascular health: Insomnia linked to greater risk of heart attack. Are there side effects from an MRI? - Coalitionbrewing.com Pain, swelling, or redness at the injection site may occur. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. Its not known if Injectafer is safe to use during pregnancy. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. Injectafer infusions are given over a period of at least 15 minutes. Also tell them about any vitamins, herbs, and supplements you use. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. If you have symptoms of a low phosphorus level, call your doctor. Read all information given to you. Their medical staff can help you set up another time to receive your Injectafer dose. However, diarrhea it isnt very common in people using Injectafer. Tell your doctor if you are pregnant or plan to become pregnant. These are not all of the side effects that may occur. The information provided is not intended to replace your healthcare provider's medical advice. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. I can't take oral supplements because they cause horrible debilitating Constipation. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. Injectafer and Feraheme are both brand-name drugs. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. (A medication class describes a group of drugs that work in the same way.). Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. Discuss the risks and benefits with your doctor. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. Talk with your doctor. You may report side effects to the FDA at 1-800-332-1088. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. endobj Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? All of the people took iron by mouth for 2 weeks. Cancer patients who have anemia and are taking an ESA. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. But if they become more severe or dont go away, talk with your doctor or pharmacist. There are currently no generic forms of either drug. The following lists contain some of the key side effects that may occur while taking Injectafer. These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. Heart failure: Could a low sodium diet sometimes do more harm than good? iron sucrose (injection) Uses, Side Effects, Dosage & Interactions Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. When the toxins are released into the air, they can be inhaled and cause irritation to the lungs. (See also Notes section.). Typical Injectafer doses for iron deficiency anemia (IDA) depends on your body weight. MNT is the registered trade mark of Healthline Media. PDF Your intravenous iron therapy - Hamilton Health Sciences If youre interested in finding an alternative to Injectafer, talk with your doctor. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. . Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. xmq92\Kz!yIP}2~(?c/JUCK2~o_N=>K$o/_7'Z+nRkKM^y{u|ZFh$v}]O~vfo=.GowGFodVj-[-~x]Kg~9H'%h={OX/#S|Mc~|]_2nv`wwotn/+$G[{hGrP}sbZG-RGf#l~~l|Qnccml_iPy]G\17c,yPF[28z&I'+B(?rrvi,G?}/;'?;pm>?.i42ONmk~ai_u0z9o_? Learn how to store and discard medical supplies safely. Iron infusion side effects vary depending on which form is being used. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing These pregnancy-related problems include preterm delivery and low birth weight of your infant. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable. (A generic drug is an exact copy of the active drug in a brand-name medication.). Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. It is important to get each dose of this medication as scheduled. <> Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. In severe cases, it can cause asthma-like symptoms, such as wheezing and difficulty breathing. The following information describes dosages that are commonly used or recommended. (For more information on Venofer, see the Injectafer vs. Venofer section above). This gives a total cumulative dose of 1,500 mg of Injectafer. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. Venofer injection contains iron sucrose, a form of the mineral iron. It is given into a vein for a period of time. (Hemoglobin is a protein thats found in red blood cells.). Talk to your pharmacist for more details. (Hemoglobin is a protein thats found in your red blood cells.). In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). People in the study received treatment with either Injectafer or Venofer. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. administered at your doctors office or an infusion center. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. 12 Medicines That Could Help, List Venofer Vial side effects by likelihood and severity. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). Injectafer begins working as soon as it enters your body. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time.